With the deployment of 5G and the 6G vision being developed, the main challenges for SMARTNESS are how to design and operate cloud computing infrastructures and networks with adequate capabilities to leverage the next generation of Internet services and applications. The scope of end-to-end services at the Internet scale is exceptionally broad and requires contributions across multiple disciplines along with large investments in capital and human resources. SMARTNESS aims to explore well-planned opportunities through an appropriate methodology based on the confluence of Research Strands (RS) designed to successfully impact world-class research and innovation through Scientific and Technological Advancements (STA) to address challenging use cases in Internet scenarios for industry and society with a vision on the horizon for the year 2030.